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Using ChatGPT in Life Sciences: Key Application Areas and Use Cases
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Using ChatGPT in Life Sciences: Key Application Areas and Use Cases

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20 Apr 2023

GenAI has emerged as a transformative force in life sciences, unlocking opportunities across research, commercial, medical, and regulatory functions. In my earlier blog, I highlighted a few considerations that are critical for the adoption of GenAI technologies like ChatGPT in pharma.

Pfizer’s "Charlie" assistant and Moderna’s "mChat" offer real-world examples of ChatGPT applications in life sciences. Many pharma organizations have started using ChatGPT for smarter HCP engagement and medical content personalization. According to McKinsey research, GenAI is expected to produce $60 billion to $110 billion in annual value across the pharmaceutical value chain.

In this blog, I’ll focus on the practical side: the use cases where GenAI delivers the most value today, and where it’s gaining momentum. These examples are best viewed through the lens of broader business processes and not just isolated technologies.

Visualizing prioritization: A framework for high-impact GenAI use cases

To guide where to start with GenAI, frameworks like the one below help life sciences leaders assess and prioritize use cases across business impact, feasibility, and strategic alignment.

Value LeverValue DriverValue DescriptionImpact ValueImpact Level
1 Minor3 Moderate5 SignificantEnter Score
Business ValueCost SavingsTarget average savings per year; only realized cost savings count, FTE savings to be put in reduction of process resources≤$50k≤$500k>$500k1
Strategic RelevanceAlignment with company goals/visionIndirect impact on company goals/visionDirect impact on company goals/visionDirect impact on multiple company goals/vision5
Time to clinical trial impactTarget reduction of time to clinical trial initiation or completion compared to status quo≤10%10-30%>30%1
Competitive advantageImprovement in benchmark metrics for this project in comparison to industry standardsNegligible improvement of performanceConsistent improvement of performanceSubstantial improvement of performance1
Risk reductionComplianceImprovement in adherence to existing regulations and processNegligible or no impact on complianceMeasurable increase in complianceIncrease in compliance across areas3
QualityImprovement in quality of deliverablesNegligible or no impactMeasurable quality improvementSignificant improvement in quality1
VariabilityImprovement in Consistency of deliverablesNegligible or no impactMeasurable reductionSignificant reduction in variability5
Efficiency improvementIncrease in throughputIncrease in throughput per process execution≤10%10-30%>30%3
Reduction of process resourcesReduction in FTEs, materials, time etc., per process execution≤10%10-30%>30%5
Increase in robustness (intelligence)Improvement in overall product process, e.g. workflow/ elimination of administrative tasksNegligible improvement in overall process effectivenessMeasurable improvement in overall process effectivenessSubstantial improvement in overall process effectiveness5
ScalabilityTransferability of the solution across other use cases in the organizationIsolated use case2-5 use cases>5 use cases5

Personalizing Customer Journey Maps with ChatGPT

In the experience economy, pharmaceutical companies face the challenge of building personalized customer journey maps in an omnichannel world. Traditionally, this was approached through Next Best Action models, but these often-lacked flexibility and scalability.

ChatGPT provides a more dynamic, cost-effective alternative. It enables the creation of personalized journey maps and associated omnichannel plans for a defined customer segment. This saves a significant amount of time and effort while offering a cost-effective option vis-à-vis traditional methods that require high investment.

By carefully setting up the context and guardrails, you can ensure that the technology understands the intent of the question and provides consistent responses. With this foundation in place, ChatGPT can then be used to develop detailed journey maps and plans that cater to each customer segment and persona.

Intelligent Chatbot for Real-time Patient Interaction

Conversational AI / Chatbots have been around for a long time. Now, GenAI offers you the ability to build your own chatbot and scale it to the next level. One example I was personally involved in was building a robust interactive chat functionality in a matter of days instead of months.

Today, ChatGPT can be deployed to power intelligent virtual assistants that support patients across various touchpoints. One of the most promising applications is in pharmacovigilance. By guiding conversations and extracting key information from natural language inputs, ChatGPT can capture and structure adverse event (AE) data efficiently reducing manual follow-ups and accelerating downstream processing in systems like Oracle Argus Safety.

Recent Indegene pilots have demonstrated 30–40% reduction in follow-up workload by integrating ChatGPT for AE intake and medical narrative creation.

ChatGPT can double up as a call centre/chat agent in other domain areas, with a carefully defined context preventing the AI from providing incorrect information. By guiding the conversation and asking relevant questions, ChatGPT can collect valuable information from users (patients) and AI-driven insights in medical research in real-time.

The true power of ChatGPT lies in its ability to parse sentences and extract the required information from users' responses, even if they are not formatted as data inputs. Once the AI engine has collected all the necessary information, it can be converted into a structured format that can be easily fed into a database or system.

Other promising use cases of ChatGPT in Life Sciences:

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Safety Signals: Used in literature screening and narrative summarization to proactively identify potential adverse events.
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Drug discovery: ChatGPT for medical literature analysis helps researchers identify potential drug targets, understand molecular mechanisms, and generate hypotheses for further investigation. Drug discovery with ChatGPT offers a powerful tool for exploring scientific literature, enabling researchers to leverage its capabilities in uncovering valuable insights and accelerating the drug development process
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Clinical trial optimization: GPT models are helping sponsors simulate protocol feasibility, match patient profiles, and auto-generate inclusion/exclusion criteria summaries.
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Clinical data management: ChatGPT can automate data conversion by taking multiple different formats of case report forms (CRFs), analyzing data from different sources, and providing a unified data story that is aligned with the selected standard. Manual tasks of aggregating, cleaning, and transforming data can be automated with a high level of accuracy
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Labelling & Regulatory compliance: LLMs are being deployed for HA query clustering, label harmonization, and converting protocol information into lay summaries. In a recent engagement, Indegene partnered with a German biotech company to explore GenAI use cases across regulatory functions. Through a series of co-creation workshops, HA query response automation emerged as a high-impact opportunity. Indegene helped build and implement a GenAI model that could auto-draft responses based on regulatory precedent and regional compliance norms. Additionally, a secure, searchable repository of CMC (Chemistry, Manufacturing, and Controls) data was developed, allowing authorized teams quick access to historical records and reducing response timelines. This showcases the value of ChatGPT in pharma regulatory operations, not just for automation but for accelerating accuracy, compliance, and knowledge reuse at scale.
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Medical Writing: ChatGPT can automate the labor-intensive task of analyzing research reports and writing an easy-to-read summary for HCPs based on the specific queries that a life sciences organization received from HCPs
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Patient education and support: ChatGPT can be utilized to create personalized educational materials for patients, helping them understand their condition and treatment options better. It can also offer real-time support through chat interfaces, answering common questions and promptly addressing concerns.
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Marketing and sales optimization: ChatGPT can help life sciences companies develop tailored marketing strategies and sales plans by analyzing customer segments, preferences, and behaviors. It can also assist in creating personalized content, promotions, and communication to engage customers more effectively by using ChatGPT for patient engagement.For example, Indegene partnered with a global healthcare leader to implement a customized GenAI ROI Framework. This proprietary tool helped assess and prioritize GenAI use cases across the content lifecycle evaluating factors like investment, savings, tech compatibility, and synergy across channels.The result? A phased roadmap that aligned quick wins with long-term strategic goals, driving focused investment toward the highest-ROI opportunities and enhancing overall content efficiency and effectiveness.This real-world case study shows how ChatGPT and GenAI use cases in pharma marketing can go beyond automation to create measurable business impact.
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Post-market surveillance: ChatGPT can be used to monitor social media, news articles, and other sources of information to identify potential safety concerns or emerging trends related to pharmaceutical products. This enables companies to take proactive measures to address any issues or capitalize on new opportunities.
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Diagnosis and Disease Identification: Leveraging its natural language processing capabilities, ChatGPT can analyze patient data, symptoms, and medical histories to provide valuable insights for healthcare professionals. This can streamline the diagnostic process, leading to more accurate and efficient identification of various medical conditions.
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Medical Imaging: ChatGPT's applications can contribute to the interpretation and analysis of complex visual data. By integrating with medical imaging technologies, ChatGPT assists radiologists and clinicians in interpreting scans, identifying anomalies, and generating detailed reports. This collaborative approach enhances the accuracy and speed of medical image analysis, potentially revolutionizing the diagnostic capabilities of healthcare professionals.
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Healthcare provider support: ChatGPT can function as an intelligent virtual assistant for healthcare providers, offering real-time support in areas such as drug dosing, interactions, and contraindications. This can help improve patient care and reduce the risk of errors

Final Thoughts

The practical applicability of ChatGPT in pharma is expanding rapidly. With ChatGPT and GenAI use cases in pharma moving from POCs to scaled deployments, the next frontier is responsible adoption.

It’s not just about deploying tools but also building institutional knowledge and governance to scale safely. As seen with leaders like Moderna, Pfizer, and J&J, the ones who are investing in talent, frameworks, and trust are unlocking real business value.

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